IPSS-R Prognostic Values
BONE MARROW BLASTS
BONE MARROW BLASTS
Blasts, also called myeloblasts, are immature blood cells that do not function properly. These young blood cells are produced by stem cells. Too many blast cells interfere with the production of red blood cells, white blood cells and platelets.
Healthy people have very few blasts in their bone marrow (<3%). The percentage of blasts in the bone marrow impacts prognosis. The higher the percentage of blasts the higher the score on the IPSS-R.
Prognostic Values for Determining IPSS-R Score
| Value/Score | 0 | 0.5 | 1 | 1.5 | 2 | 3 | 4 |
|---|---|---|---|---|---|---|---|
| Cytogenetics Risk Group | Very Good | Good | Intermediate | Poor | Very Poor | ||
| Blasts (%) | <2% | >2%-<5% | 5-10% | >10% | |||
| Hemoglobin (g/dL) | >10 | 8-<10 | <8 | ||||
| Platelets | >100,000 | 50,000-<100,000 | <50,000 | ||||
| ANC | >0.8 | <0.8 |
