DO YOU KNOW YOUR MDS SUBTYPE, IPSS-R SCORE AND GENE MUTATION PROFILE?
MDS treatment is individualized based on a patient’s subtype, IPSS-R score and, to some extent, genetic mutation. This knowledge will empower patients and their caregivers to take a more active role in decisions about their treatment and advocate for appropriate treatments that may prolong their life and improve their quality of life. The following information is designed to help you understand how your subtype and IPSS-R score are determined, as well as general information on genetic mutations commonly found in MDS and the importance of genetic testing for these mutations.
Knowing your subtype, IPSS-R score and gene mutation profile will help facilitate discussions with your healthcare provider on what this means for you personally and help select the best treatment options.
The IPSS-R is a classification system used by doctors to help predict a person’s risk of developing AML and overall survival without treatment.
MDS is classified into several different subtypes based on the following features: Blood cell counts, Percentage of blasts in the bone marrow, and Cytogenetics.
Genetic mutations occur when a gene is damaged and alters the genetic message. Mutations can potentially identify effective therapies to treat your disease.